There's a bug in iRedAdmin-0.2 (open source edition), it will reset SQL column `mailbox.isadmin=0` after changing password.
Please fix it manually with SQL command:
mysql> USE vmail;
mysql> UPDATE mailbox SET isadmin=1 WHERE username='postmaster@xxxx';
This bug was fixed in iRedAdmin-0.2.1 (open source edition), upgrade tutorial is mentioned in iRedMail upgrade tutorial here:
http://www.iredmail.org/wiki/index.php? … test_0.2.1